Primary Osteoarthritic knee Kallgren-
Conditions
Interventions
Transdermal microneedle patch with Ketorolac 1ml(30mg/ml),Transdermal microneedle patch
Experimental Drug,Placebo Comparator No treatment
Transdermal microneedle patch with NSAID,Transdermal microneedle patch
Sponsors
none
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with primary osteoarthritic knee Kallgren-Lawrence classification I-II.
Exclusion criteria
Exclusion criteria: patient with inflammatory arthritis, septic arthritis, skin infection, liver and renal insufficiency. patient who underwent intra-articular hyaluronic acid within 6months and steroid injection within 3months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| knee synovial thickness 0, 1, 2, 4 weeks millimeter | — |
Secondary
| Measure | Time frame |
|---|---|
| knee pain 0, 1, 2, 4 weeks VAS score,WOMAC 0, 1, 2, 4 weeks modified Thai WOMAC score | — |
Countries
ไทย
Contacts
Public ContactMongkon pisuttanawat
Hip and Knee Fellowship
Outcome results
None listed