DM with cardiac autonomic neuropathy and elderly patient are the risk of intraoperative hypotension. Postinduction hypotension lead to severe complication e.g. .MI, stroke, AKI so anesthesiologist ar DM, Cardiac autonomic neuropathy, postinduction hypotension, Eldery, General anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 65 year-old 2. DM type II 3. Elective surgery under general anesthesia with oroendotracheal tube 4. ASA II-III
Exclusion criteria
Exclusion criteria: 1.ICU care prior to OR 2. On ECMO 3. On vasoactive drug 4. U/D; Coronary artery disease 5. U/D; CVA 6. Cardiac arrhythmia 7. Intubation prior to OR 8. Difficult intubation 9. Plan rapid sequence induction 10. EF < 35% 11. BMI < 16 or > 35 12. Albumin < 2 13. Plan for combine GA and RA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare incidence of post induction hypotension in eldery with DM with/without CAN Intraoperative peroid Incidence | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare probability of vasoactive drug administration of both groups. Intraoperative peroid Incidence,Compare probability of vasoactive drug administration of both groups. Intraoperative peroid Incidence | — |
Countries
Thailand
Contacts
Prince of Songkla university