Intradialytic hypertension Intradialytic hypertension Dialysate potassium concentration
Conditions
Interventions
Patients in intervention arm will be prescribed 3 mmol/L of dialysate potassium concentration in every hemodialysis sessions during study period.,Patients in intervention arm will be prescribed 2 mmol
Experimental Other,Active Comparator Other
Dialysate potassium concentration 3 mmol/L,Dialysate potassium concentration 2 mmol/L
Sponsors
Lampang hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. ESRD patients (defined by Kidney Disease Initiative Global Outcome (KDIGO) Guideline 2012) requiring chronic hemodialysis 2. Hemodialysis vintage more than 12 weeks 3. Hemodialysis with at least 2 sessions per week 4. History of intradialytic hypertension (defined by an increase in systolic blood pressure >15 mmHg or mean arterial pressure >10 mmHg during hemodialysis) at least 30% of their dialysis sessions during the past 12 weeks
Exclusion criteria
Exclusion criteria: 1. Serum potassium >5.5 mEq/L or <2.5 mEq/L 2. Active cardiac, pulmonary or hepatobiliary tract disease 3. Active infection or sepsis 4. Active malignancy 5. Cirrhosis 6. Prior prescribed with dialysate potassium concentration 3 mmol/L in past 2 weeks 7. Interdialytic weight gain more than 6%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intradialytic hemodynamic parameters During hemodialysis Blood pressure (mmHg), heart rate (bpm) | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of events of intradilytic hypertension During hemodialysis Number of events (%) ,Serum potassium End of study mEq/L | — |
Countries
Thailand
Contacts
Public ContactThanawat Vongchaiudomchoke
Department of internal medicine, Lampang hospital
Outcome results
None listed