Patients,
Conditions
Interventions
PSV mode : Ps 5 PEEP 5 FiO2 0.3-0.4 to keep SpO2 not less than 90% for 30 minutes,T-piece 10LPM FiO2 0.3-0.4 to keep SpO2 not less than 90% for 30 minutes
Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery
30-minute SBT with PSV,30-minute SBT wIth T-piece
Sponsors
None
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years or older undergoing mechanical ventilation for at least 24 hours 2. Patients who fulfilled the weaning criteria: (all are included) (1) resolution or improvement of the condition leading to intubation (2) hemodynamic stability, defined as systolic blood pressure between 90 and 160 mm Hg and heart rate less than 140/min without vasopressors or with low doses of vasopressors (3) Glasgow Coma Scale score of 13 or greater (4) respiratory stability, defined as oxygen saturation >90% with fraction of inspired oxygen [FiO2] not more than 0.4, respiratory rate <35/min, spontaneous tidal volume >5 mL/kg (5) non copious secretion (not more than 1 aspiration within 2hours)
Exclusion criteria
Exclusion criteria: 1. Patients with tracheostomy 2. Patients with Upper airway obstruction 3. Patients denied to re-intubation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Extubation success rate 72 hr after extubation without reintubation Observe and record results by physicians | — |
Secondary
| Measure | Time frame |
|---|---|
| Spontaneous breathing trial success rate 30min after complete Spontaneous breathing trial Observe and record results by physicians,Time to reintubation 7days after extubation Observe and record results by physicians,Reasons for reintubation 7 days after extubation without reintubation Observe and record results by physicians | — |
Countries
Thailand
Contacts
Public ContactYanisa Kluanwan
King Chulalongkorn Memorial Hospital
Outcome results
None listed