A physiologic study of the effects of real-time waveform analysis (IntelliSync+) on breathing pattern, inspiratory effort, and synchronization in mechanically ventilated patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200528003

Enrollment

Registered

2020-05-28

Start date

2020-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanically ventilated patients Asynchrony Inspiratory effort Pressure support ventilation

Interventions

Intellisync&#45

i for 15 min then Intellisync&#45

i/c for 15 min and then Intellisync&#45

e for 15 min,Intellisync&#45

i/c for 15 min then Intellisync&#45

i for 15 min and then Intellisync&#45

c for 15 min then Intellisync&#45

i for 15 min

Experimental Other,Experimental Other,Experimental Other

i,Intellisync i/c,Intellisync&#45

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age >/= 18 years 2. Mechanically ventilated patients with pressure support ventilation: PS </= 16 cmH2O, PEEP </= 10 cmH2O and FiO2 </= 0.6 3. Receiving mechanical ventilation for at least 24 hours

Exclusion criteria

Exclusion criteria: 1. Unstabel hemodynamics 2. Moderate to severe respiratory distress 3. Severe acid-base disturbance 4. Tracheostomy 5. Contraindication for esophageal balloon catheter insertion 6. Pregnancy 7. Refuse to participate

Design outcomes

Primary

Measure	Time frame
Trigger delay time 15 minutes ventilator and esophageal pressure waveforms	—

Secondary

Measure	Time frame
esophageal pressure time product 15 minutes ventilator and esophageal pressure waveforms,asynchrony index 15 minutes ventilator and esophageal pressure waveforms	—

Countries

Thailand

Contacts

Public ContactDr. Nuttapol Rittayamai

Faculty of Medicine Siriraj Hospital, Mahidol University

nuttapol.rit@mahidol.ac.th024197757

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026