Skip to content

Comparison of lower motor power between 0.0625% Bupivacaine plus Fentanyl 2 µg/ml and 0.1% Bupivacaine plus Fentanyl 2 µg/ml for continuous epidural analgesia in patients undergoing gynecologic oncology surgery: A Randomized Controlled Trial Study

Comparison of lower motor power between 0.0625% Bupivacaine plus Fentanyl 2 µg/ml and 0.1% Bupivacaine plus Fentanyl 2 µg/ml for continuous epidural analgesia in patients undergoing gynecologic oncology surgery: A Randomized Controlled Trial Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200528002
Enrollment
110
Registered
2020-05-28
Start date
2020-05-28
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing gynecologic oncology surgery Epidural analgesia&#44

Interventions

Give 0.1% Bupivacaine plus fentanyl 2 mcg/ml 8 ml/hr epidural postoperatively,Give 0.0625% Bupivacaine plus fentanyl 2 mcg/ml 8 ml/hr epidural postoperatively
Experimental Drug,Experimental Drug
0.1% Bupivacaine+fentanyl 2 mcg/ml,0.0625% Bupivacaine+fentanyl 2 mcg/ml

Sponsors

Rajavithi hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age 20-75 years Gynecologic oncology patients undergoing general anesthesia at Rajavithi hospital ASA physical status 1-2 Patient can normally ambulate. Patient accept to recruit in the study.

Exclusion criteria

Exclusion criteria: Patients who have contraindication for epidural catheter insertion - Coagulopathy - Infection at insertion site - lower motor weakness - Severe mitral stenosis, severe aortic stenosis - Increased intracranial pressure Allergy to the drugs that were used in the study NYHC >=2 Patients with comorbid disease such as stroke, spinal cord disease, myocardial ischemia

Design outcomes

Primary

MeasureTime frame
Lower motor weakness at 24- hour postoperative period Modified Bromage scale

Secondary

MeasureTime frame
Pain after surgery 24, 48-hour postoperatively Numerical rating scale,Ambulation after surgery 24,48-hour postoperatively Successful 3-meter walk with assistant,Blood pressure 6, 24, 48-hour postoperatively Systolic blood pressure, Diastolic blood pressure,Nausea and vomiting 6, 24, 48-hour postoperatively Incidence ,Itching 6, 24, 48-hour postoperatively Incidence

Countries

Thailand

Contacts

Public ContactViranut Tirasuntornwong

Rajavithi hospital

Ton_832@yahoo.com0814508215

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026