Adult patients (Aged 20-65 years) Good general health (ASA 1, 2) and not a contraindication for minor surgery The diagnosis and indications for guided bone regeneration Dental implants, Guided bone regeneration
Conditions
Interventions
Synthetic resorbable membrane,Collagen membrane
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Polycaprolactone membrane,Cytoplast RTM
Sponsors
Faculty of Dentistry, Thammasat University
Faculty of Dentistry,
Thammasat University
Eligibility
Sex/Gender
Male
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Adult patients (age 20-70 years) 2. Good general health (ASA 1, 2) and not a contraindication for minor surgery 3. The diagnosis and indications for a particulate bone substitute include: a. Alveolar bone defects, class 2 (Benic & Hammerle 2014). b. The edentulous area allows placement of at least one standard implant and not exceed a two-tooth span. 4. Patients who needed reconstruction of the edentulous sites with simultaneous implant placement 5. Controlled periodontitis. 6. Smoking history <10 cigarettes per day. For the subject who smokes but less than 10 cigarettes per day is requested to stop smoking two weeks before and after bone block graft surgery and implant placement 7. No history of allergy or hypersensitivity to any materials to be used in the study. 8. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Presence of relevant medical conditions: Patients with bone disease, osteoporosis, uncontrolled diabetes mellitus, unstable or life-threatening conditions, or requiring antibiotic prophylaxis. Patients with medication of drugs influencing the bone metabolism or use of bisphosphonates. 2. Pregnancy or lactation. 3. Patients who have poor oral hygiene. 4. Patients with active infection or pathologic lesions prior to operation 5. Patients who cannot take impression (both conventional and digital) and CBCT 6. History of malignancy, radiotherapy, or chemotherapy for malignancy in the past 5 years. 7. History of autoimmune disease or long-term prescribed of nonsteroidal anti-inflammatory drugs 8. Unwillingness to return for the follow-up examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone thickness and soft tissue dimensional change 1 year after loading Clinical,Radiogragphic | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical parameters, marginal bone level, Implant stability, wound healing, esthetic score 1 year after loading Radiographic | — |
Countries
Thailand
Contacts
Public ContactThun Kusirisin
Faculty of Dentistry, Thammasat University
Outcome results
None listed