Overweight,
Conditions
Interventions
Placebo starch capsule,20 mg of simvastatin positive control drug,1.6 g of garlic extract ,1.6 g of O. indicum extract (high dose),0.5 g of O. indicum extract (low dose)
Placebo Comparator No treatment,Active Comparator Drug,Active Comparator Dietary Supplement,Experimental Dietary Supplement,Experimental Dietary Supplement
Placebo,SIM,GE,OIE(H),OIE(L)
Sponsors
Suranaree University of Technology
Suranaree University of Technology
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria: men and women 30 to 60 years of age, affected by overweight or obesity, with the body mass index (BMI) of 25–35 kg/m2 and without a previous diagnosis of cardiovascular disease
Exclusion criteria
Exclusion criteria: (1) coronary heart diseases, e.g. heart failure, myocardial infarction, arrhythmia; (2) endocrine disease, e.g. sex gland disorder, thyroid disorder, and pituitary disorder; (3) pregnant or lactating women; (4) taking medications or supplements and herbals that might interfere with blood glucose and lipid measurements. Subjects were excluded if they had side effects from the extract.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| anti-hyperlipidemia effect 12 week (measure every month) Serum lipid (Cholesterol, Triglyceride, LDL-C and HDL-C) measurement | — |
Secondary
| Measure | Time frame |
|---|---|
| anti-hyperglycemia effect 12 week (measure every month) oral glucose tolerance testing | — |
Countries
Thailand
Contacts
Public ContactGriangsak Eumkeb
Suranaree University of Teachnology
Outcome results
None listed