Early neonatal sepsis Early neonatal sepsis,
Conditions
Interventions
At risk of early neonatal sepsis as stated in inclusion criteria
Other
Preterm newborn infants GA < 35 weeks
Sponsors
Siriraj Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inborn preterm infants of gestational age less than 35 weeks 2. Sterile cord cutting 3. Infants have at least one of risk factors for early neonatal sepsis below 3.1 Maternal chorioamnionitis diagnosed clinically by obstetricians 3.2 Maternal fever > 38oC within 24 hours before delivery 3.3 Presence of labour pain 3.4 Premature rupture of membranes 3.5 Cervical insufficiency 3.6 Induction of labor 3.7 Unexplained fetal distress
Exclusion criteria
Exclusion criteria: 1. Presence of symptoms suspected to result from of early onset neonatal sepsis within 3 hours after birth 2. Lethal congenital anomalies 3. Congenital infection from toxoplasmosis, rubella, cytomegalovirus, herpes simplex, syphilis, and zika virus 4. Maternal age < 18 years old 5. Parents cannot fluently communicate in Thai 6. Not consented 7. Incomplete data
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of early onset neonatal sepsis 72 hours after birth Positive hemoculture or cerebrospinal fluid culture within 72 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of antibiotic administration in the at-risk infants within 72 hours after birth Antibiotics administration according to attending physicians decision | — |
Countries
Thailand
Contacts
Public ContactBuranee Yangthara
Siriraj Hospital
Outcome results
None listed