์Neonatal Early Onset Sepsis Neonatal sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Infants born at Vajira hospital, gestational age above 35 weeks and one of the followings; 1.Infants whose mother has a fever greater than or equal to 38 degrees Celsius 2.Maternal vaginal and anal cultures are positive for GBS 3.Premature rupture of membrane for more than 18 hours after delivery 4.Mothers with suspected intra-amniotic infection 5.Preterm less than 37 week's gestation 6.infants with symptoms compatible with EOS within 72 hour after symptoms include respiratory distress, drowsiness, apnea, temperature instability and feeding intolerance
Exclusion criteria
Exclusion criteria: 1.Infants with congenital anomalies 2.Chromosomal abnormalities 3.Infants born outside Vajira Hospital 4.Maternal information is not available
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of culture negative sepsis At the begining of study, within 7 days, within 60 days Number of patients with culture negative sepsis (clinical sepsis determined by physician + neonatal | — |
Secondary
| Measure | Time frame |
|---|---|
| Rate of early onset sepsis (EOS) At the begining of study, within 7 days, within 60 days Number of patients with early onset sepsis (patients with positive blood culture) | — |
Countries
Thailand
Contacts
Faculty of Medicine Vajira Hospital, Navamindradhiraj University