Comparing the success of partial pulpotomy applied with MTA, Acemannan and Biodentine

MTA, Acemannan and Biodentine demonstrated similar partial pulpotomy success rates in deep-caries lesions in lower primary molars with reversible pulpitis : a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200513001

Enrollment

Unknown

Registered

2020-05-13

Start date

2014-10-14

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep carious lesion with reversible pulpitis No abnormal signs and symptoms Acemannan partial pulpotomy primary teeth MTA Biodentine

Interventions

Mineral trioxide aggregate (MTA) is an alternative material to calcium hydroxide. It composed of calcium &#44

silica and bismuth. MTA has a high success rate in pulp treatment due to its properties&#44

such as sealing ability and biocompatibility. ,Biodentineâ„¢ is a tricalcium silicate&#45

based cement developed as a dressing material. This material has many biological properties similar to MTA&#44

however&#44

it has an improved shorter setting time&#44

good handling properties&#44

and lower cost.,acemannan is a polysaccharide extracted from local aloe vera that has been used as wound healing agent for a long time. It is biocompatible and has been evaluated its use as pulp capp

Active Comparator Other,Active Comparator Other,Active Comparator Other

Mineral trioxide aggregate ,Biodentine,acemannan

Eligibility

Sex/Gender

All

Age

3 Years to 8 Years

Inclusion criteria

Inclusion criteria: The clinical inclusion criteria were: mandibular primary molars with a deep carious lesion with reversible pulpitis and sufficient tooth structure to be restored with a stainless steel crown, without spontaneous pain or abnormal signs and symptoms, tenderness to percussion, abnormal tooth mobility, abscess or sinus tract opening. The radiographic inclusion criteria were: a deep carious lesion approximately 1 mm from the pulp, without pathology at the periapical or furcation area, internal or external root resorption, physiologic root resorption not more than one-third of the root length, pulp obliteration, and a continuous lamina dura.

Exclusion criteria

Exclusion criteria: No sign in consent form Presentation of any medical problems affect dental treatment

Design outcomes

Primary

Measure	Time frame
The success of partial pulpotomy evaluation at 6 ,12,18 and 24 months Clinical and radiographic success outcomes,The success of partial pulpotomy evaluation at 6 ,12,18 and 24 months Clinical and radiographic success outcomes	—

Secondary

Measure	Time frame
Radiographic failure evaluation at 6 ,12,18 and 24 months Radiographic success outcomes	—

Countries

Thailand

Contacts

Public ContactPraparat Tungjitphianpong

Unaffiliated

parate25@hotmail.com+66+87+0980080

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026

Comparing the success of partial pulpotomy applied with MTA&#44; Acemannan and Biodentine