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the Effect of Prescribing Zinc Sulfate on Improving the Clinical Symptoms of Pneumonia in 2-59-Month-Old Children

the Effect of Prescribing Zinc Sulfate on Improving the Clinical Symptoms of Pneumonia in 2-59-Month-Old Children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200512005
Enrollment
Unknown
Registered
2020-05-12
Start date
2011-10-03
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tachypnea (number of breaths)&#44

Interventions

The control group received placebo (similar to the zinc sulfate syrup in terms of color and taste&#44
made by Farabi pharmaceutical company). ,received zinc sulfate (made by Farabi pharmaceutical company) as 10 mg/day in children younger than one&#44
and 20 mg/day in children above one year old every 12 hours (during hospitalization and most 10 days)
Active Comparator No treatment,Active Comparator Drug

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Months to 59 Months

Inclusion criteria

Inclusion criteria: children 2-59-months old with a diagnosis of pneumonia based on history and clinical examination, and if necessary, chest x-ray by a pediatrician

Exclusion criteria

Exclusion criteria: Children with chronic diseases such as immunodeficiency, cystic fibrosis, renal diseases, chronic pulmonary diseases, malnutrition and chronic diarrhea, acute severe infection, history of hospitalization over the past three months, use of immunosuppressive drugs, and history of taking zinc supplements over the past two weeks were excluded. Chronic diarrhea was defined as diarrhea for more than 14 days. Malnutrition was characterized based on clinical symptoms of kwashiorkor or Marasmus or FTT. Severe infection meant severe sepsis. Further, the patients suspect of foreign bodies and gastroesophageal reflux were also excluded.

Design outcomes

Primary

MeasureTime frame
Clinical Symptoms of Pneumonia During hospitalization, every 12 hours tachypnea, duration of fever, coughs, intercostal retraction, hypoxia, crackles-wheezing, and durati

Secondary

MeasureTime frame
N/A N/A N/A

Countries

iran

Contacts

Public ContactFarhad Heydarian

Associate Professor of Pediatrics,Department of Pediatrics, Faculty of Medicine, Mashhad University

Heydarianf@mums.ac.ir+985138411538

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026