A Comparison of the Effectiveness of 5% Lidocaine Medicated Plaster and EMLA Cream for Decreasing Pain on Venous Cannulation for Fluid Administration

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200429002

Enrollment

120

Registered

2020-04-29

Start date

2020-05-18

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Decreasing pain on venous cannulation Decreasing sensation on the dorsum of the hand Lidocaine Prilocaine EMLA Plaster Sensation Pain Venous cannulation Monofilament

Interventions

Applying EMLA on left hand >1 hour and venous cannulation on left hand. Applying lidocaine plaster on right hand >7 hours. Monofilament tests on both hands before and after applying both medications,A

Active Comparator Drug,Active Comparator Drug,Experimental Drug,Experimental Drug

EMLA: Left hand (EL),EMLA: Right hand (ER),Lidocaine plaster: Left hand (LL),Lidocaine plaster: Right hand (LR)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 yr or more No difficult venous catheter insertion both dorsum of hands Admit 1 day or more before surgery ASA physical status 1-3 Written inform consent

Exclusion criteria

Exclusion criteria: Neurological disorders and abnormal perception of skin Disease which affects the perception of skin such as diabetes Abnormal skin lesion on the dorsum of the hand such as ulcers, scars, swelling Contraindication for venous catheter insertion on the dorsum of the hands such as axillary lymph node dissection, AVBG, SVC obstruction Allergy to lidocaine, prilocaine, and preservatives Unable to communicate Patient refusing

Design outcomes

Primary

Measure	Time frame
Pain on venous cannulation Morning of surgery (after applying of EMLA at least 1 hour or lidocaine plaster at least 7 hours) Visual analogue scale (VAS)	—

Secondary

Measure	Time frame
The monofilament-pick detected sensation Baseline and before venous cannulation (after applying of EMLA >1 hour or lidocaine plaster >7 hour) The Semmes Weinstein monofilament examination,Side effects During applying both medications until 24 hour after removing Number of count,Skin wrinkling Baseline and before venous cannulation (after applying of EMLA >1 hour or lidocaine plaster >7 hour) Wrinkling scale,Procedurer's satisfaction After venous cannulation Satisfaction score (0-10),Number of attempts of venous cannulation After venous cannulaation Number of count	—

Measure

Time frame

The monofilament-pick detected sensation Baseline and before venous cannulation (after applying of EMLA >1 hour or lidocaine plaster >7 hour) The Semmes Weinstein monofilament examination,Side effects During applying both medications until 24 hour after removing Number of count,Skin wrinkling Baseline and before venous cannulation (after applying of EMLA >1 hour or lidocaine plaster >7 hour) Wrinkling scale,Procedurer's satisfaction After venous cannulation Satisfaction score (0-10),Number of attempts of venous cannulation After venous cannulaation Number of count

—

Countries

Thailand

Contacts

Public ContactNarut Ruananukun

Ramathibodi Hospital

aek_narut@hotmail.com0815954599

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026