The efficacy of topical tranexamic acid in reducing blood loss after direct anterior hip replacement in osteoporotic femoral neck fracture patients

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200428006

Enrollment

Registered

2020-04-28

Start date

2018-11-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total hemoglobin loss total pack red cell transfusion during perioperative peroid incidence of deep vein thrombosis topical tranexamic acid hip fracture hip replacement blood loss complication

Interventions

500 mg injection intra&#45

articular tranxamic 20 ml acid into hip joint after anterior bases&#45

hip muscle sparing approach in osteoporotic femoral neck fracture patients,20 ml injection of normal slaine into hip joint

Experimental Procedure/Surgery,Experimental Procedure/Surgery

intra&#45

articular tranxamic acid ,normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: osteoporotic hip fracture muscle spairing surgical hip approach underwent hip replacement

Exclusion criteria

Exclusion criteria: pre-exiting deep vein thrombosis multiple fracture bleeding disorder non-stoping anti-platelet prior surgery

Design outcomes

Primary

Measure	Time frame
total hemoglobin loss at post op day 0, day 1, day 2 and day 3 g/dl	—

Secondary

Measure	Time frame
total blood transfusion rate perioperative peroid unit,symptomatic deep vein thrombosis perioperative peroid patient number	—

Countries

Thailand

Contacts

Public ContactKulapat Chulsomlee

orthopedic department, Ramathibodi Hospital

superparn006@gmail.com0863668449

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026