Skip to content

Evaluation of peri-implant crevicular fluid biomarkers and marginal bone loss in platform-switched and non-platform-switched implants: a randomised prospective clinical study

Evaluation of peri-implant crevicular fluid biomarkers and marginal bone loss in platform-switched and non-platform-switched implants: a randomised prospective clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200425004
Enrollment
Unknown
Registered
2020-04-25
Start date
2014-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

missing teeth dental implants&#44

Interventions

dental implant application using traditional abutments to the posterior site&#44
marginal bone level,dental implant application using platform switch abutments to the posterior site
Active Comparator Device,Active Comparator Device

Sponsors

istanbul university scientific research project
Lead Sponsor
istanbul university
Collaborator

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: an implant site without acute infection or bone defects; a bone crest ≥7 mm; a full-mouth plaque score (modified plaque index [mPI]) and full-mouth bleeding score (bleeding on probing [BOP]) ≤25%; ≤10 cigarettes per day if a smoker; and a peri-implant keratinised tissue width ≥2 mm.

Exclusion criteria

Exclusion criteria: systemic medical conditions such as diabetes and any medication that could influence healing of soft or hard tissue. full-mouth plaque score (modified plaque index [mPI]) and full-mouth bleeding score (bleeding on probing [BOP]) more than 25%; 10 and more cigarettes per day if a smoker; and a peri-implant keratinised tissue width less than 2 mm.

Design outcomes

Primary

MeasureTime frame
PICF LTB4 levels 1 year Elisa

Secondary

MeasureTime frame
PICF MMP8/TIMP1 levels 1 year Elisa

Countries

turkey

Contacts

Public Contactgamze adem siyli

istanbul university

gamzezeynepadem@gmail.com00905418038548

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026