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Peripapillary and macular vessel density change after tumor removal in compressive optic neuropathy

Peripapillary and macular vessel density change after surgery in tumor patients with compressive optic neuropathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20200424002
Enrollment
35
Registered
2020-04-24
Start date
2020-04-27
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All consecutive patients diagnosed as compressive optic neuropathy and confirmed by imaging in Songklanagarind hospital between April 2020 to December 2021 Compressive optic neuropathy Peripapillary capillary density Optical coherence tomography angiography

Interventions

All consecutive patients diagnosed as compressive optic neuropathy and confirmed by imaging
Basic Science
Patients with compressive optic neuropathy from tumor

Sponsors

Faculty of Medicine, Prince of Songkla University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Patient was diagnosed with compressive optic neuropathy and had visual field or visual acuity abnormality. 2) Tumor compressed the anterior visual pathway including optic nerve or optic chiasm and confirmed by neuroimaging. 3) Patient is undergoing tumor removal surgery. 4) Age 18-60 years old

Exclusion criteria

Exclusion criteria: 1) Patient with poor image quality including images with poor clarity, motion artifact, and scans 2) Patient has an unreliable preop visual acuity or visual field test which are 30% false positive, false negative, or fixation loss rate 3) Evidence of other ocular diseases such as glaucoma, or coexisting retinal pathologies that may cause the visual abnormality or affected retinal and choroidal vasculature 4) Patient with poor cooperation or sitting disability

Design outcomes

Primary

MeasureTime frame
Percentage of the peripapillary vessel density After patient complete the measurements Optical coherence tomography angiography(OCTA)

Secondary

MeasureTime frame
Percentage of the macular vessel density After patient complete the measurements Optical coherence tomography angiography(OCTA)

Countries

Thailand

Contacts

Public ContactJuthamat Witthayaweerasak

Faculty of Medicine, Prince of Songkla University

leklikachang@gmail.com0815992099

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026