Aspiration carbohydrate loading orthognathic surgery
Conditions
Interventions
Patient will be treated with 12.5% carbohydrate drink (50 gm of glucose in 400 ml of water) at 3 hour prior to surgery,Patient will be treated with plain water (400 ml) at 3 hour prior to surgery
Experimental Procedure/Surgery,Placebo Comparator Procedure/Surgery
Preoperative carbohydrate loading group,Placebo group
Sponsors
Faculty of Dentistry, Chiang Mai University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patient is healthy or presented with well-controlled systemic disease (ASA class I,II) 2. Patient will undergo orthognathic surgery 3. Patient gives consent to participate this study
Exclusion criteria
Exclusion criteria: 1. Patient has history of gastroesophageal reflux disease 2. Patient has history of upper GI tract surgery 3. Patient has history of metabolic disease 4. Patient has history of smoking 5. Patient has history of pregnancy 6. Patient is presented with uncontrolled systemic disease (ASA class III,IV) 7. Patient is presented with body mass index more than 25
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of plasma interleukin-6 3 hours prior to surgery and 24 hours after surgery Enzyme-linked immunosorbent assay (ELISA) ,Homeostatic model assessment-insulin resistance 3 hours prior to surgery and 24 hours after surgery Enzyme-linked immunosorbent assay (ELISA) | — |
Secondary
| Measure | Time frame |
|---|---|
| time to readiness for discharge from post-anesthetic care unit after surgery minute (count),length of stay in hospital After surgery to discharge day (count),quality of recovery 24 hours after surgery Thai QoR-35 score,complications within 3 weeks after surgery Surgical and anesthetic complication (count) | — |
Countries
Thailand
Contacts
Public ContactWarit Powcharoen
Chiang Mai University
Outcome results
None listed