The Clinical Outcome of Emergency versus Urgent Endoscopic Retrograde Cholangiopancreatoscopy in Patients with Acute Cholangitis: A Randomized Control Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200416004

Enrollment

250

Registered

2020-04-16

Start date

2020-07-15

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute cholangitis cholangitis ERCP

Interventions

ERCP within 12 hours in patients with severe (TG2018) acute cholangitis ERCP within 24 hours in patients with moderate (TG2018) acute cholangitis ,ERCP within 48 hours in patients with severe (TG2018

Experimental Procedure/Surgery,Active Comparator Procedure/Surgery

Emergency ERCP,Urgent ERCP

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute cholangitis (Definite or suspected diagnosis) according to TG2018 Moderate or severe according to TG2018 severity grading criteria

Exclusion criteria

Exclusion criteria: Preexisting biliary drainage Coexisting acute cholecystitis Coexisting liver abscess Coexisitng acute pancreatitis Upper GI obstruction precluding ERCP Surgically altered anatomy Pregnancy Not willing to participate

Design outcomes

Primary

Measure	Time frame
30 day-Mortailty 30 days Clinical evaluation	—

Secondary

Measure	Time frame
Organ failure 72 hours TG2018 definition,Inflammatory marker 72 hours serum CRP and procalcitonin level ,Severity of disease 72 hours APACHE II score ,Length of hospital stay At hospital discharge Hospitalization day count ,post ERCP adverse event 30 days TG2018 definition	—

Countries

Thailand

Contacts

Public ContactNonthalee Pausawasdi

Faculty of Medicine Siriraj Hospital, Mahidol University

nonthaleep7@gmail.com024197281

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026