Seborrhea Chitosan Sebum production oily skin seborrhea
Conditions
Interventions
Chitosan will be applied on their entire face.,Placebo will be applied on their entire face.
Sponsors
Dermatology division, Department of internal medicine, King Chulalongkorn Memorial Hospital
Dermatology division,
Department of internal medicine,
King Chulalongkorn Memorial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Healthy volunteers aged 18-40 years with seborrhea 2.Volunteers who have well adherence and can be followed up as appointed
Exclusion criteria
Exclusion criteria: 1.Volunteers with chronic kidney or liver disease 2.Volunteers with known history of chitosan allergy 3.Volunteers with history of topical retinoids or topical antisebum production usage within 1 month prior to enrollment 4.Volunteers with history of oral retinoids,spironolactone,oral contraceptive or anti-androgenic effect drugs usage within 3 months prior to enrollment 5.Volunteers with history of phototherapy or botulinum toxin injection within 6 months prior to enrollment 6.Volunteers with history of topical corticosteroid usage at the site of evaluation within 2 week prior to enrollment 7.Volunteers with history of oral corticosteroid treatment or intralesional corticosteroid injection at the site of evaluation within 4 week prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sebum week 4,8 Sebumeter | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect Week 4,8 Questionnaire | — |
Countries
Thailand
Contacts
Public ContactChanat Kumtornrut
Faculty of Medicine,Chulalongkorn university
Outcome results
None listed