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The efficacy and safety of Snail soothing and repairing cream on corneometry and transepidermal water loss after ablative fractional CO2 laser: a split face randomized double blind placebo-controlled trial

The efficacy and safety of Snail soothing and repairing cream on corneometry and transepidermal water loss after ablative fractional CO2 laser: a split face randomized double blind placebo-controlled trial

Status
Recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200413004
Enrollment
22
Registered
2020-04-13
Start date
2020-02-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

skin restoration Snail soothing and repairing cream Wound healing Ablative fractional CO2 laser Acne scar

Interventions

Snail soothing and reparing cream will be applied twice daily to the half of the face,Placebo will be applied twice daily to the half of the face
Experimental Drug,Placebo Comparator Other
Snail soothing and reparing cream,Placebo

Sponsors

Dermatology division, Department of internal medicine, King Chulalongkorn Memorial Hospital
Lead Sponsor
Dermatology division&#44
Collaborator
Department of internal medicine&#44
Collaborator
King Chulalongkorn Memorial Hospital
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Healthy volunteers aged 18-50 years 2.Volunteers who have well adherence and can be followed up as appointed

Exclusion criteria

Exclusion criteria: 1.Pregnancy or breastfeeding 2.Volunteers who have been received Botox and filler treatment for 3 months before enrollment 3.Volunteers who have history of photosensitive skin conditions 4.Volunteers who have history of psoriasis 5.Volunteers who have history of anesthetic agent and components of Snail soothing and repairing cream allergy 6.Volunteers who have history of skin cancers,herpes simplex infection and active dermatitis 7.Volunteers who have received Anticoagulants and anti platelet treatment

Design outcomes

Primary

MeasureTime frame
Skin hydration day 7 and day 14 Corneometry,Transepidermal water loss day 7 and day 14 Tewameter

Secondary

MeasureTime frame
Clinical outcomes: erythema,swelling,crusting and pruritus day 7 and day 14 Questionnaire

Countries

Thailand

Contacts

Public ContactPawinee Rerknimitr

Faculty of Medicine,Chulalongkorn University

pawineererk@yahoo.co.th022564253

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026