Reduction of melasma. melasma laser hyperpigmentation
Conditions
Interventions
One side of the face was randomized to apply 0.15% ITR containing product for 12 weeks. The Low fluence QS laser was performed every 1 week for 5 sessions. ,Cream base was used for placebo. The other
Active Comparator Drug,Placebo Comparator Drug
ITR and low-
fluence QS Nd:YAG,Placebo and low-
fluence QS Nd:YAG
Sponsors
Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital
Division of Dermatology,
Department of medicine,
Faculty of Medicine,
Ramathibodi hospital
Eligibility
Sex/Gender
All
Age
18 Years to 0 Years
Inclusion criteria
Inclusion criteria: Symmetrical mixed type melasma on both malar areas
Exclusion criteria
Exclusion criteria: Pregnant or lactating women Having a dermatological condition on the treating area History of topical or systemic therapy for melasma within 1 mont History of laser therapy within 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean relative lightness index evaluate at every visit colorimeter (DSM II ColorMeter®),Clinical changes evaluate at every visit Melasma Area and Severity Index on the malar area (MASIm),patient satisfaction scores evaluate at every visit visual analogue scale on improvement of melasma | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events evaluate at every visit Dermatologist evaluation and patients' feedback | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Faculty of Medicine, Ramathibodi hospital
Outcome results
None listed