general examination in normal range normal eye examination OCTA optical coherence tomohraphy angiography retinal vascular hemodynamic retinal vessel Retinal vasculature body position head position normal population healthy population effect
Conditions
Interventions
volunteers will be taken OCTA picture of bot eyes in 5 position
1.Upright position
2.Prone position immediately(at o min)
3.Prone position at next 10 minutes(at 10th minute)
4.Prone position with head
Basic Science
Healthy population
Sponsors
Ratchadapisek sompoch
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1 Healthy populations – normal physical and normal eye examination (vital signs keep body temperature <37.8c , blood pressure < 140/90 mmHg, heart rate 60 – 120 beats/minute) 2 Age above or equal to 18 years 3 Normal range intraocular pressure in sitting position 4 Refractive error range from -3.00 diopter to +3.00 diopter
Exclusion criteria
Exclusion criteria: 1 History of systemic vascular disease, hypertension, diabetic mellitus, cerebrovascular disease, cardiovascular disease, peripheral vascular disease 2 History of ocular disease that affect to visual acuity and ocular circulation 3 History of smoking, 4 Contraindications to prone position (cervical spine disease, cervical or back muscle strain, wound at chest or abdomen, history of congestive heart failure and obstructive sleep apnea) 5 Body weight greater than or equal to 100kg or BMI(body mass index) greater than or equal to 30 6 Waist circumference greater than or equal to 36 inches in male and greater than or equal to 32 inches in female 7 Corneal problems that cannot measure intraocular pressure by handheld tonometer (corneal scar, corneal edema) 8 Allergy to 1%tropicamide eyedrop 9 Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| macular perfusion density at study date optical coherence tomography angiography | — |
Secondary
| Measure | Time frame |
|---|---|
| macular vessel density at study date optical coherence tomography angiography,foveal avascular zone area at study date optical coherence tomography angiography,Central subfield thickness at study date optical coherence tomography angiography program,Single point subfoveal choroidal thickness at study date optical coherence tomography angiography program,Intraocular pressure at study date measure by handheld tonometry,Systemic blood pressure at study date measure by sphygmomanometer,Ocular perfusion pressure at study date by calculation,optic nerve head perfusion at study date optical coherence tomography angiography,optic nerve head flux index at study date optical coherence tomography angiography,foveal avascular zone perimeter at study date optical coherence tomography angiography,foveal avascular zone circularity at study date optical coherence tomography angiography | — |
Countries
Thailand
Contacts
Public ContactApisuda Wattanapreechanon
Faculty of medicine, Chulalongkorn university
Outcome results
None listed