Cough after awakening from general anesthesia,
Conditions
Interventions
A comparison of different dose intravenous lidocaine for prevent cough and sore throat after awakening from general anesthesia,
a double blind randomized control trial
Experimental Drug
A comparison of different dose intravenous lidocaine for prevent cough and sore throat after awakeni
Sponsors
Phramongkutklao Hospital
Phramongkutklao Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: • agree to receive treatment according to the research plan • undergoing surgery By choosing the method of anesthesia and endotracheal tube • Age 18-65 years • ASA I-II (patients who do not have any underlying disease or have underlying disease that can control the symptoms and do not have severe complications) • able to read, write and understand Thai
Exclusion criteria
Exclusion criteria: • Refusing to participate in research • have a history of hypersensitivity to lidocaine or other local anesthetics • Patients with abnormal liver and kidney function • Patients with congestive heart failure, recent myocardial infarction and cardiac arrhythmia such as AV block, atria fibrillation, Ventricular tachycardia • Problems with communication using language (language barrier) • Patients with a history of asthma or emphysema • Patients with a history of upper respiratory infections within 2 weeks. • Patients with high blood pressure and receiving ACEI • Patients who are pregnant Or is breast-feeding • The patient undergoes emergency surgery. • • Patients with adverse effects from coughing, such as patients with increased intracranial pressure and rupture globe • ASA classification 3 and above
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of intravenous different lidocaine dose that use before extubation about the cough 05/12/2020 four-point scale postoperative room, grade 0 = no coughing, grade 1 = moderate coughing, grade 2 = m | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of intravenous different lidocaine dose that use before extubation about sore throat 05/12/2020 Four-point scale at 1 hr. postoperative, grade 0 no sore throat, grade1 mild, grade2 moderate, grade | — |
Countries
Thailand
Contacts
Public ContactChanathip Ajavananda
Phramongkutklao Hospital
Outcome results
None listed