Comparison postoperative delirium within 24 hours between ketamine and propofol as a main anesthetic agent during cardiopulmonary bypass machine

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200324003

Enrollment

Registered

2020-03-24

Start date

2019-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative stroke death re&#45

Interventions

ketamine 1&#45

2 mg/kg/hr continuous infusion during CPB,propofol 25&#45

100 mcg/kg/min continuous infusion during CPB

Active Comparator Drug,Active Comparator Drug

ketamine,propofol

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: patients who are elderly (â‰¥65 years old) of both genders. patients who have less than 4 euroscore. patient without language barrier. patients who undergo cardiac operation performed under general anesthesia with cardiopulmonary bypass.

Exclusion criteria

Exclusion criteria: patients who known preoperative cognitive disorder (dementia, cognitive impairment) patients who've got positive CAM and RASS patients who have psychiatric or mental disorder patients who have cerebrovascular disease or carotid disease patients who undergo aortic surgery patients who died intra-operatively or within the first 24 hours after the procedure and re-operative patients.

Design outcomes

Primary

Measure	Time frame
postoperative delirium 24 hours post-operation CAM-ICU and Richmond Agitation-Sedation Scale	—

Secondary

Measure	Time frame
none none none	—

Countries

thailand

Contacts

Public Contactsutira siripoonyothai

Faculty of Medicine, Chulalongkorn University

pulpul74@hotmail.com0850709966

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026