An efficacy of tranexamic acid added in 2% lidocaine with epinephrine administered subcutaneously in upper blepharoplasty : A double blind randomized control trial

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200319009

Enrollment

Registered

2020-03-19

Start date

2020-03-26

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative bleeding in upper blepharoplasty Upper blepharoplasty Tranexamic acid Bleeding

Interventions

Pre operative local anesthesia with lidocaine&#44

adrenaline and tranexamic acid in upper blepharoplasty(study side).,Pre operative local anesthesia with lidocaine and adrenaline in upper blepharoplasty(control side).

Experimental Drug,Placebo Comparator Drug

Local anesthesia with adrenaline and tranexamic acid,Local anesthesia with adrenaline

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Upper blepharoplasty patients in Ramathibodi hospital.

Exclusion criteria

Exclusion criteria: Tranexamic acid allergy Ptosis Pregnancy History of bleeding disorder On anticoagulant agent Uncontrolled hypertension Revision upper eye lids surgery History of thrombocytosis History of seizure Active infection at surgical site

Design outcomes

Primary

Measure	Time frame
Intra-operative blood loss Intraoperation Weight of gauze with blood	—

Secondary

Measure	Time frame
Post operative ecchymosis and swelling Post operative 1 week Area measurement	—

Countries

Thailand

Contacts

Public ContactThitinan Chaichumporn

Mahidol university

Jannythiti@gmail.com0898156739

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026