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EFFECT OF GUTTA-PERCHA SOLVENTS ON POSTOPERATIVE PAIN AFTER ROOT CANAL RETREATMENT: A RANDOMIZED CLINICAL TRIAL

EFFECT OF GUTTA-PERCHA SOLVENTS ON POSTOPERATIVE PAIN AFTER ROOT CANAL RETREATMENT: A RANDOMIZED CLINICAL TRIAL

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200319008
Enrollment
Unknown
Registered
2020-03-19
Start date
2019-09-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain after non&#45

Interventions

using solvent (GuttaClear) in procedure ,not using solvent (GuttaClear) in procedure
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
solvent,non&#45

Sponsors

Faculty of Graduate Studies
Lead Sponsor
Faculty of Graduate Studies
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Participants aged more than 18 years with healthy physical status or well-controlled systematic diseases, according to class I or II from ASA classification will be enrolled. In addition, they should not be contra-indicated with medication used in this study (ibuprofen), i.e., drug allergy or related systemic conditions. All included participants will have a previously treated endodontic single-root tooth with the need of retreatment and all those teeth must be restorable. Moreover, old root canal filling materials must be located at 1 to 3 mm from the radiographic apex in the periapical radiograph.

Exclusion criteria

Exclusion criteria: Any tooth presenting an open apex, root resorption or root perforation would be excluded. In addition, participants presenting pre-operative pain and/or swelling at the appointment visit, taking analgesics or antibiotics less than one week before appointment visit or experiencing problems in completing the pain questionnaires would be excluded. Moreover, a tooth which does not contain gutta-percha or cannot be patent through the apex at the appointment visit will be excluded, too.

Design outcomes

Primary

MeasureTime frame
postoperative pain 3 days NRS score

Secondary

MeasureTime frame
the amount of medication intake 3 days number

Countries

Thailand

Contacts

Public ContactDuangrat Sirijindamai

Mahidol University

Duangrat.sir@gmail.com+6622007764

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026