Use of Alginate Carboxymethylcellulose Hyaluronic Acid for Prevention of Intrauterine Adhesion after Vacuum Aspiration in Patients with First Trimester Abortion: A Prospective study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200314005

Enrollment

Registered

2020-03-14

Start date

2019-09-01

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion

Interventions

Vacuum aspiration only&#44

no drug,Applied drug after vacuum aspiration

No Intervention No treatment,Experimental Drug

No Med,alginate carboxymethylcellulose hyaluronic acid gel

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: - Pregnant woman with gestational age of 13 weeks or less with blighted ovum or incomplete abortions or inevitable abortions or embryonic death with manual vacuum aspiration or electric vacuum aspiration following abortion in outpatient department or inpatient department or emergency department - No history of uterine curettage, pelvic infection, intrauterine surgery, IUD used, and endometriosis - Not allergy to Hyaluronic acid, Carboxymethylcellulose or Alginate

Exclusion criteria

Exclusion criteria: - Need to D&C after the procedure - Hormonal contraception used during the research period - Pregnant before the scheduled of hysteroscopy - Complication during or after the procedure such as uterine perforation, infection, or incomplete abortion

Design outcomes

Primary

Measure	Time frame
Formation of IUAs 2-3 months Hysteroscopy	—

Secondary

Measure	Time frame
Severity of IUAs 2-3 months Hysteroscopy	—

Countries

Thailand

Contacts

Public ContactWoradej Hongsakoorn

Ramathibodi hospital

Tom.woradej@gmail.com0855532896

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026