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Anti-sarcopenic Effect of Branched-chain Amino Acid Supplementation in Patients Receiving High Dose Corticosteroids: A Randomized Controlled Trial

Anti-sarcopenic Effect of Branched-chain Amino Acid Supplementation in Patients Receiving High Dose Corticosteroids: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200314002
Enrollment
Unknown
Registered
2020-03-14
Start date
2014-08-06
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients that received high dose corticosteroids&#44

Interventions

None,Oral 7.5 g BCAA supplementation
Control group,BCAA group

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients that received high dose corticosteroids, prednisolone > 0.5 mg/kg/day, an age of 18 years or more, no risk factors of myopathy such as sepsis or cirrhosis, no contraindication for long term steroid used, no contraindication for bioelectrical impedance analysis (BIA) and DEXA scan were eligible for enrollment

Exclusion criteria

Exclusion criteria: Orthopedic limitations, poor communication and compliance, history of used herbal medicine.

Design outcomes

Primary

MeasureTime frame
Muscle mass and nutritional status in patients receiving high dose of corticosteroids at 12 weekat after start intervention Muscle mass form DXA Scan,Muscle mass and nutritional status in patients receiving high dose of corticosteroids at 12 weekat after start intervention Muscle mass form DXA Scan

Secondary

MeasureTime frame
Factors that affect muscle mass in patients receiving high dose of corticosteroids at 12 weekat after start intervention Laboratory test

Countries

Thailand

Contacts

Public ContactNeti Sunsandee

Department of Internal Medicine, Phramongkutklao Hospital

Neti.sunsandee@gmail.com0867575012

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026