Apply to basic benefits in screening people at high risk of liver cell cancer at the national level PIVKA-
Conditions
Interventions
1.Annual health check-
ups that have normal blood tests,
including high-
frequency ultrasound,
do not have a lump suspected of primary liver cancer
2.Patients with hepatitis B virus infection Hepatitis C And cirrhosis patients from various causes
3.Patients who have detected a lump in the liver
ray of the upper abdomen.
Treatment
Patients whom had risks for HCC
Sponsors
None
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years and older 2. The annual health check-up who has regular blood tests including high frequency sound tests and no lumps suspected of primary liver cancer 3. Chronic hepatitis B patients Males aged over 40 years and females aged over 50 or have direct relatives with primary liver cancer 4.Chronic hepatitis C patients with pathological effects of liver tissue With at least level 3 fascia Or the flexibility of the liver with transient elastography greater than or equal to 9.5 or blood Fibrotest® is greater than 0.58 regardless of whether it has been treated or not. 5. Patients who have been diagnosed with liver cirrhosis for any reason From the examination of high frequency sound waves Radiographic images using a computer or an X-ray of the upper abdomen. 6. Patients who have detected a lump in the liver greater than or equal to 1 cm in size from the ultrasound Radiographic images using a computer or an X-ray of the upper abdomen.
Exclusion criteria
Exclusion criteria: 1. pregnant patients 2. Patients with jaundice from biliary tract obstruction 3. Patients who received vitamin K during the study 4. Patients receiving warfarin While studying 5. Other types of cancer detected While diagnosing primary liver cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary liver cancer diagnosis 3 year PIVKA-II Test µTASWako i30, ELECSYS, ARCHITECT AFP-L3 | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactWattana Sukeepaisarnjaroen
Khonkaen University
Outcome results
None listed