Elective major surgery Sleep disruption Delirium Prolonged mechanical ventilation
Conditions
Interventions
This is a single-
group study. All subjects recruited will be later classified whether they are in good sleep by polysomnographic finding.
Diagnostic
Study group
Sponsors
Faculty of Medicine, Chualongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Adult patients (at least 18 years old) undergoing elective major surgery 2. Requires postoperative ICU admission with mechanical ventilation
Exclusion criteria
Exclusion criteria: 1. Previously diagnosed sleep related disorder 2. History of sleep-aiding medication in 1 month before enrollment 3. Previous use of transquilizers, antidepressants, anti-epeliptics, or other psychotropic medications 4. Cannot communicate in Thai 5. History of elicit drug use including alcohol more than 7 standard drink per week for female or 14 standard drink for male 6. Central nervous system disorders or previous traumatic brain injury or history of seizure 7. Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BIS index prediciting good sleep quality During first night after surgery Acquiring BIS data and analyzed against polysomnography | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean BIS index in each stage of sleep During first night after surgery Acquiring BIS data and analyzed against polysomnography,Mean BIS index change predicting polysomnographic arousal During first night after surgery Acquiring BIS data and analyzed against polysomnography,Time on mechanical ventilation After surgery Counting hours that patients was on mechanical ventilation ,Length of ICU stay After surgery Counting hours that patients was in ICU ,Length of hospital stay In hospital admission Counting days patients spent in hospital | — |
Contacts
Public ContactPongpol Sirilaksanamanon
Chulalongkorn University
Outcome results
None listed