Local allergic rhinitis Chronic rhinitis,
Conditions
Interventions
patient s who are clinical alllergic rhinitis with negative skin prick test
Diagnostic
clinical alllergic rhinitis with negative skin prick test
Sponsors
FACULTY of medicine , CU
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Clinical chronic rhinitis [runny nose, nasal stuffiness, sneezing] 2.Age 18 yr old and above 3.Negative SPT or IDT or serum specific IgE
Exclusion criteria
Exclusion criteria: .1.Previous use - antihistamines and/or vasoconstrictors within a week - intranasal corticosteroid within a month - systemic corticosteroid within 3 months 2.unstable systemic disease 3.pregnant or lactating women 4.undergone nasal surgery within the previous 3 months 5.chronic rhinosinusitis and/or nasal polyps (confirmed by rigid endoscopy, paranasal x ray, and/or computed tomography) 6.exposed to chemical irritants or cigarette smoke 7. Respiratory tract infection within 4 wks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nasal eosinophil count At the beginning of study eosinophil count from nasal scrapping | — |
Secondary
| Measure | Time frame |
|---|---|
| Cytokine[IgE] At the beginning of study immunocap[PCR],nasal imflammatory cells At the beginning of study cell count for nasal scrapping | — |
Countries
Thailand
Contacts
Public ContactLalita Prathanee
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed