The effects of mechanical cough assist on rate of reintubation in patients with ineffective cough

effects of mechanical cough assist on rate of reintubation in patients with ineffective cough

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200215002

Enrollment

Registered

2020-02-15

Start date

2019-04-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with mechanical ventilation more than 48 hours&#44

Interventions

the patient received five sessions of the airway clearance procedure with MI&#45

E (1 session before extubation via endotracheal tube and 4 sessions via face mask during the 48&#45

hour post&#45

extubation period),standard post extubation care

Active Comparator Device,No Intervention No treatment

MI&#45

E,control

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: aged 18 or older with mechanical ventilation more than 48 hours, planed extubation and passed spontaneous breathing trial (SBT) and cough leak test, with ineffective cough measured by cough peak flow < 270 LPM.

Exclusion criteria

Exclusion criteria: pneumothorax, hemodynamic instability, hemoptysis, unfollow to command, gastrointestinal hemorrhage, bronchospasm, upper airway obstruction

Design outcomes

Primary

Measure	Time frame
rate of reintubation 48 hour after extubation number of reintubation	—

Secondary

Measure	Time frame
cough peak flow 48 hour after extubation peak flow meter	—

Countries

Thailand

Contacts

Public Contactnicha ruamsap

Division of Pulmonary and Critical Care Medicine

nicharuamsap@gmail.com0865688430

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026