Minimum effective volume of crystalloid to prevent spinal induced hypotension during elective cesarean delivery: An up-down sequential allocation design.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200213001

Enrollment

100

Registered

2020-02-13

Start date

2020-01-25

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal hypotension spinal anesthesia crystalloid co-load hypotension elective cesarean delivery

Interventions

IV Acetar co-loading is given within 5-10 min. After co-loading,IV Acetar infuses at rate 100 ml/hr &amp

5%DN/2 IV 20 ml/hr

No Intervention Biological/Vaccine

Crystalloid fluid

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Singleton term pregnancy Elective cesarean delivery American Society of Anesthesiology classification I-II

Exclusion criteria

Exclusion criteria: Pregnant woman who has hypertensive disorder Cardiac pathologies/ Fluid overload and contraindicated for fluid loading Pregnant woman with extreme height (< 150 cm, > 190 cm) BMI > 35 kg/m2 at the time of delivery Patient who has inadequate spinal anesthesia or high spinal/ total spinal anesthesia Refusal to participate the study

Design outcomes

Primary

Measure	Time frame
Volume of crystalloid fluid At the end of operation Measuring by infusion pump	—

Secondary

Measure	Time frame
Hemodynamic parameters At the start of operation,2.5,5,7.5,10,12.5,15,17.5,20 mins after start operation Non invasive cardiac output monitoring	—

Countries

Thailand

Contacts

Public ContactLisa Sangkum

022011513

lisa.sangkum@gmail.com0989075899

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026