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Safety assessment and consumption effects of cashew leaf extract capsules(single dose) on stress hormone, stress response and quality of life of male with shift work

Safety assessment and consumption effects of cashew leaf extract capsules(single dose) on stress hormone, stress response and quality of life of male with shift work

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200128001
Enrollment
Unknown
Registered
2020-01-28
Start date
2020-01-21
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy conditions Cashew leaf extract Male with shift work Stress hormone Stress response

Interventions

Subjects are received the placebo product which has same color and smell look like capsules containing the extract of cashew leaf,Subjects are received capsules containing the extract of cashew leaf 2
000 mg
Placebo,Capsules containing the extract of cashew leaf 2&#44

Sponsors

MARK ONE INNOVATION CENTER COMPANY LIMITED.
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 55 Years

Inclusion criteria

Inclusion criteria: -Male with shift work aged between 25-55 years old -ISMA Stress Questionnaire scores >14

Exclusion criteria

Exclusion criteria: -Diagnosed with cardiovascular diseases, respiratory diseases, neuropsychological diseases, head injury, diabetes mellitus, liver disease, cancer, autoimmune diseases and hematological disorder -Smoking more than 10 pieces/day -Alcohol addiction -Volunteers who require supplements or herbs or drugs at least 1 months before participating in this study and during the trial

Design outcomes

Primary

MeasureTime frame
Salivary Cortisol 2 hours Elisa method

Secondary

MeasureTime frame
Stress response 2 hours ISMA Stress Questionnaire,Monoamine oxidase activities in serum 2 hours Elisa method,The changes of hematological and clinical chemistry parameters 2 hours laboratory,Safety evaluation and side effect 2 hours Questionnaire,Electrocardiogram (EKG) 2 hours Electrocardiograph

Countries

ไทย

Contacts

Public ContactWipawee Thukhammee

Khon Kaen University

wipath@kku.ac.th+6685-0016805

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026