healthy human botulinum toxin A,
Conditions
Interventions
botulinum toxin A (Botox Allergan) total 20 unit (5 unit per 1 cm in length) intradermal injection within 14 days of operation date ,proceed with regular surgery.
botulinum toxin group,control group
Sponsors
Thammasat University
Thammasat University
Eligibility
Sex/Gender
Male
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Thai people who undergoing inframammary incision breast augmentation
Exclusion criteria
Exclusion criteria: 1. patients with dermatologic diseases with koebner phenomenon such as lichen planus, psoriasis, vitiligo 2. neuromuscular junction diseases such as myasthenia gravis, Lambert-Eaton syndrome 3. family history of keloids 4. botulinum toxin, aminoglycosides, penicillamines, cholinesterase inhibitors, quinine, calcium channel blocker allergy 5. patients with past medical history such as DM, HT, CKD, chronic liver disease, vasculitis, thrombosis or embolism on any site, cancer 6. current receiving immunosuppressive medication 7. pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of botulinum toxin A in scar prevention 3, 6, 9 months Vancouver scar scale (VSS), Patient and observer scar assessment scale (POSAS) | — |
Secondary
| Measure | Time frame |
|---|---|
| elasticity, scar width and thickness, safety of botulinum toxin A 3, 6, 9 months Antera3D, Cutometer, photograph | — |
Countries
Thailand
Contacts
Public ContactWongsiya Viarasilpa
Thammasat University
Outcome results
None listed