Clitoria ternatea Flower Extract Attenuates Postprandial Lipemia and Increases Plasma Antioxidant Status Responses to a High-Fat Meal Challenge in Overweight and Obese Participants

Effect of Clitoria Ternatea flower extract on postprandial plasma lipidemia, antioxidant and inflammatory response following high-fat meal consumption in overweight/obese men.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20200114006

Enrollment

Registered

2020-01-14

Start date

2019-09-27

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

High&#45

fat meal (50% fat of total calories),a HF meal plus 1 g of Clitoria ternatea flower extact,a HF meal plus 2 g of Clitoria ternatea flower extact

Placebo Comparator No treatment,Active Comparator Dietary Supplement,Active Comparator Dietary Supplement

fat (HF) meal,HF/1 CTE,HF/2 CTE

Eligibility

Sex/Gender

Male

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: - BMI 23-30 kg/m2 - Fasting blood glucose < 100 mg/dl - Blood urea nitrogen (BUN) 8-24 mg/dL - Creatinine 0.84 - 1.21 mg/dL - Aspartate transaminase (AST) 8 - 48 U/L - Alanine transaminase (ALT) 7 - 55 U/L - Blood pressure < 120/80 mmHg - White blood cell count 3,500 - 10,500 cells/mcL - No smoker and alcohol users

Exclusion criteria

Exclusion criteria: - Chronic diseases such as diabetes mellitus, hypercholesterolemia, liver and kidney diseases etc. - Allergy to cow milk, wheat, gluten, butter - Using any dietary supplements or medications related to antioxidants

Design outcomes

Primary

Measure	Time frame
Postprandial plasma lipid, antioxidant status and imflammatory cytokines 0, 30, 60, 90, 120, 180, 240, 300 and 360 min Biochemistry measurement	—

Secondary

Measure	Time frame
Gene expression of oxidative stress and inflammatory response genes in PBMC 0, 180 and 360 min qPCR	—

Countries

Thailand

Contacts

Public ContactSirichai Adisakwattana

Chulalongkorn University

sirichai.a@chula.ac.th022181099

Outcome results