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Efficacy of perineural dexamethasone with lidocaine and bupivacaine mixture in axillary brachial plexus block for decreasing duration of motor blockage in patient undergoing surgery for fracture distal end radius: A randomized controlled trial

Efficacy of perineural dexamethasone with lidocaine and bupivacaine mixture in axillary brachial plexus block for decreasing duration of motor blockage in patient undergoing surgery for fracture distal end radius: A randomized controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200114003
Enrollment
70
Registered
2020-01-14
Start date
2020-05-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Too long duration of motor blockage Distal end radius fracture Axillary brachial plexus block

Interventions

1.2% Lidocaine + 0.2% Bupivacaine + Dexamethasone 5 mg total 21 ml,0.5% bupivacaine 20 ml + NSS 1 ml total 21 ml
Active Comparator Drug,Placebo Comparator Drug

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 20-85 years old 2. Known diagnosed as closed fracture distal end of radius 3. ASA physical status I-III as American Society of Anesthesiologists classification 4. Indication for axillary brachial plexus block for perioperative analgesia for surgery < 3 hours

Exclusion criteria

Exclusion criteria: 1. Refusal 2. Cognitive impairment 3. Contraindication for axillary brachial plexus block 4. Anatomy deformity in blocking area 5. Neuropathy or neurological deficit 6. DM with HbA1C > 7.5 % 7. GFR < 50 ml/min 8. Body weight below 35 kg 9. Known allergy to intervention agents 10. Chronic pain (take oral morphine > 20 mg/day)

Design outcomes

Primary

MeasureTime frame
Duration for motor power of hand grip recovery 24 hours Time as hour

Secondary

MeasureTime frame
Duration of analgesia 24 hours Time as hours

Contacts

Public ContactBusara Sirivanasandha

Faculty of medicine Siriraj hospital, Mahidol university

busarasiri@gmail.com085149656

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026