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The effect of two different botulinum toxin injection methods and doses to treat gummy smile caused by hyperfunctional muscles

The effect of two different botulinum toxin injection methods and doses to treat gummy smile caused by hyperfunctional muscles

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20200105002
Enrollment
30
Registered
2020-01-05
Start date
2020-01-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients with excessive gingival display Excessive gingival display Botulinum toxin

Interventions

the first group will receive 2.5 IU. At one site per side (a total of two sites) The solution will be injected 3 mm lateral to the alar&#45
facial groove at the level of the nostril opening at the insertion of the levator labii superioris alaeque nasi muscle&#44
2.5IU for each side,The second group will receive botulinum toxin injection at 2 sites 5IU per side (a total of four sites) into: (1) levator labii superioris alaeque nasi with the levator labii super
the junction/approximation of the levator labii superioris and the zygomaticus minor. The dose given to each patient in this study is based on previously published information that cited a range of 2
Active Comparator Drug,Experimental Drug
injection at single site per side,injection at 2 sites per side

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: healthy patients with excessive gingival display due to muscular hyperfunction which will be determined by the degree of lip mobility

Exclusion criteria

Exclusion criteria: Patients with gingival display due to short clinical crowns or long maxilla, pregnant patients, or patients who are breastfeeding, as well as patients with neuromuscular disorders.

Design outcomes

Primary

MeasureTime frame
Amount of improvement 2 and 16 weeks The distance between the lower margin of the upper lip and the incisal edge

Secondary

MeasureTime frame
Degree of satisfaction 2 and 16 weeks 5-point aesthetic scale

Countries

Iraq

Contacts

Public ContactSalwan Bede

College of Dentistry, University of Baghdad

salwan.bede@gmail.com07906210006

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026