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Randomized trial comparing efficacy of 12.5 and 25 µg oral misoprostol 2 hourly for induction of labor

Randomized trial comparing efficacy of 12.5 and 25 µg oral misoprostol 2 hourly for induction of labor

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20191230002
Enrollment
160
Registered
2019-12-30
Start date
2018-11-02
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Induction of labor in maternal and fetal condition Induction of labor &#44

Interventions

given 12.5 micrograms of misoprostol oral every 2 hr,given 25 micrograms of misoprostol oral every 2 hr
Experimental Drug,Experimental Drug
12.5 micrograms of misoprostol,25 micrograms of misoprostol

Sponsors

Udonthani hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: women with singleton live pregnancy , Gestational age greater than or equal to 38 weeks , have indication of induction of labor , vertex presentation, normal fetal heart rate , Bishop score less than or equal to 6 point , intact membrane

Exclusion criteria

Exclusion criteria: refuse participate in research , misoprostol allergy , previous cesarean section or myomectomy ,underlying disease such as heart, renal ,liver disease ,severe preeclampsia with severe feature , Grand multiparity ,regular uterine contraction , multifetal pregnancy , active genital tract disease , DFIU and fetal anomaly , estimate fetal weight more than 4000 grams

Design outcomes

Primary

MeasureTime frame
Rate of successful induction of labor within 24 hours , comparing 12.5 and 25 µg oral misoprostol Induction time to delivery time successful induction of labor was defined as vaginal delivery within 24 hr can be achieved

Secondary

MeasureTime frame
maternal and neonatal outcome after delivery period analyzed data of maternal and neonatal outcome after delivery,rate of uterine tachysystole , rate of cesarean section after delivery period record data and analyzed data after delivery

Countries

Thailand

Contacts

Public ContactChutinan Chantarakhantee

Udonthani hospital

nami_davil@hotmail.com+66812610590

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026