Does the presence of cirrhosis influence on the mortality rate in patients with acute-on-chronic liver failure? APASL-ACLF Research Consortium study.

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

TCTR

Registry ID

TCTR20191226002

Enrollment

Unknown

Registered

2019-12-26

Start date

2009-01-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Presence of cirrhosis and its mortality influence in patients with acute&#45

Interventions

Patients who were diagnosed as having acute&#45

on&#45

chronic liver failure who had underlying liver cirrhosis,Patients who were diagnosed as having acute&#45

chronic liver failure who had underlying chronic liver disease without cirrhosis

Treatment,Treatment

Acute&#45

&#45

chronic liver failure with cirrhosis,Acute&#45

chronic liver failure without cirrhosis

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All adult patients, age above 18 years old, who were hospitalized from the emergency room or outpatient clinical due to having ACLF

Exclusion criteria

Exclusion criteria: decompensated cirrhosis, concomitant malignancy, pregnancy, severe co-morbidities (such as severe neurological deficit, poor cardiac function, chronic lung disease that limits activity in daily life, uncontrolled autoimmune diseases, etc.), chronic kidney disease and currently receive immunosuppressant

Design outcomes

Primary

Measure	Time frame
Mortality rate 28 days and 90 days Observation	—

Secondary

Measure	Time frame
Length of hospital stay 90 days Observation	—

Countries

Thailand

Contacts

Public ContactTongluk Teerasarntipan

Chulalongkorn University

kulgnoth@hotmail.com6622564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Does the presence of cirrhosis influence on the mortality rate in patients with acute&#45;on&#45;chronic liver failure? APASL&#45;ACLF Research Consortium study.