Undernutrition hemodialysis patients End stage renal disease Hemodialysis Omega-3 Fish oil Intradialytic parenteral nutrition
Conditions
Interventions
Fish oil-
containing IDPN prescribe every hemodialysis sessions,Counseling by dieticians to reach the calories goal.
containing IDPN,Intensive dietary counseling
Sponsors
Grant for research, Faculty of medicine, Chulalongkorn University
The kidney foundation of Thailand
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with maintenance chronic hemodialysis > 3 month 2. Patients who can't tolerate oral nutrition supplement 3. Patients who have spontaneous energy intake > 20 kcal/kg/day and protein > 0.8 g/kg/day after conventional dietary counseling 4. With 2/4 of Serum albumin < 3.5 g/dL Serum prealbimin < 30 mg/dL 7-point SGA category B MIS >= 5
Exclusion criteria
Exclusion criteria: 1. Serum triglyceride > 300 mg/dL 2. Blood sugar > 300 mg/dL 3. Pregnancy or lactation 4. Advanced stage malignancy 5. Current inflammation or infection such as CRBSI, tuberculosis 6. Having anti-inflammatory drugs 7. Cirrhosis 8. AIDs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum albumin 0, 3, 6 months Blood sample | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum prealbumin 0, 3, 6 months Blood sample,Somatic protein 0, 3, 6 months BIA, BCM, handgrip strength test,MIS 0, 3, 6 months Assess by dietician,SGA 7-point 0, 3, 6 months Assess by dietician,IL-6 0, 3, 6 months Blood sample,hsCRP 0, 3, 6 months Blood sample,Acyl ghrelin 0, 3, 6 months Blood sample,Leptin 0, 3, 6 months Blood sample | — |
Countries
Thailand
Contacts
Public ContactAthiphat Banjongjit
Division of nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University
Outcome results
None listed