The effect of vitamin A on intestinal mucosal injury in pediatric patients receiving hematopoietic stem cell transplantation and chemotherapy: a randomized controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20191207002

Enrollment

Registered

2019-12-07

Start date

2017-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitamin A insufficiency in pediatric hematopoietic stem cell transplant patients vitamin A supplementation&#44

Interventions

Vitamin A supplementation group received a single dose of 200000 IU of vitamin A before conditioning regimen was given,No vitamin A supplementation before conditioning regimen was given

Experimental Drug,No Intervention No treatment

Vitamin A supplementation,non&#45

vitamin A supplementation

Eligibility

Sex/Gender

All

Age

1 Years to 18 Years

Inclusion criteria

Inclusion criteria: patients age 1-18 years who underwent hematopoietic stem cell transplantation during May 2017 to August 2018 at the Bone marrow transplantation unit, Ramathibodi hospital, Thailand

Exclusion criteria

Exclusion criteria: patients received vitamin A supplementation in the previous three months

Design outcomes

Primary

Measure	Time frame
change in plasma citrulline after vitamin A supplementation and hematopietic stem cell transplant baseline, day 0 and day 7 after stem cell infusion plasma citrulline	—

Secondary

Measure	Time frame
post transplant complication and clinical of vitamin A toxicity 60 days after transplantation outcome of patients	—

Contacts

Public ContactPloy Pattanakitsakul

Faculty of medicine, Ramathibodi hospital, Mahidol university

sapp_ploy@hotmail.com0894946408

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026