Acanthosis nigricans Acanthosis nigricans,
Conditions
Interventions
the interventions involving different dosage form of topical 10% urea and topical 20% urea for treatment acanthosis nigricans,the interventions involving different dosage form of topical 10% urea and
Active Comparator Drug,Active Comparator Drug
10% urea cream, 20% urea cream
Sponsors
Faculty of Medicine, Srinakharinwirot University
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: The participants aged over 12 years with a diagnosis of acanthosis nigricans
Exclusion criteria
Exclusion criteria: - Vulnerable skin diseases - Infectious skin diseases - Other recent diseases involving the neck - Other serious medical disorders e.g. DM, liver disease - Any patients having received other therapies for up to 4 weeks prior to enrollment. - Photosensitive skin - Immunocompromised host - Pregnancy and lactation - Receiving oral retinoids - Neck tattoo
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the efficacy of 10% urea cream and 20% urea cream in the treatment of acanthosis nigricans week 0, 2, 4 and week 8 The degree of neck hyperpigmentation improvement was assessed with the Mexameter MX18 | — |
Secondary
| Measure | Time frame |
|---|---|
| The efficacy of 10% urea cream and 20% urea cream in the treatment of acanthosis nigricans week 0, 2, 4 and week 8 using the investigator’s global evaluation (IGE) | — |
Countries
Thailand
Contacts
Public ContactArucha Treesirichod
Faculty of Medicine, Srinakharinwirot University
Outcome results
None listed