Comparing the running subcuticular technique versus the Donati technique in open carpal tunnel release: a randomized controlled trial

A randomized controlled trial comparing skin closure in limited open carpal tunnel release: Running subcuticular sutures versus Donati sutures.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20191204002

Enrollment

141

Registered

2019-12-04

Start date

2020-01-13

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carpal tunnel syndrome Carpal tunnel, scar, scar evaluation, POSAS, wound closure, VAS score, functional outcome

Interventions

Donati purposing the vertical mattress skin sutures aid to precise skin edge eversion.Some studied compared single interrupted sutures and Donati sutures after open carpal tunnel release&#44

and the result showed that both Donati and single stitches are related to excellent scar formation. The Donati sutures are related to more prolonged postoperative pain. ,Running subcuticular suture te

Active Comparator Procedure/Surgery,Active Comparator Procedure/Surgery

Donati suture,Subcuticular suture

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients with carpal tunnel syndrome, based on the combination of patient's history (Pain, paresthesia and/or hypothesia in the hand in the area innervated by the median nerve), physical examination (thumb abduction weakness, thenar atrophy), and measurements of nerve conduction velocity. The patients age are range between 18 to 75 years, and have ability to complete the written inform consent. All of these patients who requires surgical decompression.

Exclusion criteria

Exclusion criteria: Exclusion criteria was included a history of lidocraine allergy, a history of wrist trauma or previous operation, a history of underlying causes of CTS, such as diabetes mellitus, pregnancy, hypothyroidism, inflammatory arthropathy ,and obesity (body mass index (BMI) >30). Patient who had a history of hypertrophic scar and had past history of wound healing problem also excluded.

Design outcomes

Primary

Measure	Time frame
surgical scar 2 weeks, 6 weeks and 3 months after operation POSAS score	—

Secondary

Measure	Time frame
VAS score and functional outcome 2 weeks, 6 weeks and 3 months after operation DASH score and VAS score	—

Countries

Thailand

Contacts

Public ContactSITTHIPHONG SUWANNAPHISIT

Faculty of Medicine, Prince of Songkla University

aunsittipong@gmail.com0909829595

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026