Prevention of incidence and severity of cough and laryngospasm
Conditions
Interventions
Injection 0.9%NaCl 2 minutes before extubation,Injection 0.25 mg/kg of propofol 2 minutes before extubation,Injected combiantion of 0.25 mg/kg of propofol /kg and of ketamine2 minutes before extubat
Sham Comparator Drug,Active Comparator Drug,Active Comparator Drug
Control group,Propofol group ,Combination group
Sponsors
Phramongkutklao Hospital
Phramongkutklao Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: ASA physical status I and II, with airway assessment of Mallampati grade 1 and 2, between the age group of 18-60 years, scheduled for elective surgeries under general anesthesia.
Exclusion criteria
Exclusion criteria: unwilling patients, history of allergy to any drug, history of bronchial asthma, chronic obstructive pulmonary disease, respiratory tract infection, impaired kidney or liver function, on angiotensin converting enzyme inhibitors, a history of hypersensitivity to local anesthetics, pregnancy and language barrier.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of coughing and laryngospasm Within 2 minutes after extubation The severity of coughing was graded as (0=no incidence of coughing, 1=only one cough, 2= two coughs | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of laryngospasm Within 2 minutes after extubation Laryngospasm was graded according as 0 = no symptoms,1=stridor , 2= total occlusion of the cords ( | — |
Countries
Thailand
Contacts
Public ContactSithapan Munjupong
Phramongkutklao hospital
Outcome results
None listed