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Urine TIMP2.IGFBP7 reflects kidney injury after moderate volume paracentesis in patients with ascites: A randomized control study

Urine TIMP-2.IGFBP7 as a predictor for acute kidney injury in cirrhotic patient receiving abdominal paracentesis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20191116003
Enrollment
30
Registered
2019-11-16
Start date
2019-11-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Cirrhotic patients who received abdominal paracentesis for 3 liters,Cirrhotic patients who received abdominal paracentesis for 5 liters
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Abdominal paracentesis 3 liters group,Abdominal paracentesis 5 liters group

Sponsors

The Gastroenterological Association of Thailand (GAT)
Lead Sponsor
Department of Medicine&#44
Collaborator
Phramongkutklao Hospital
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Aged equal or more than 18 years old - Cirrhosis with diuretic-resistance ascites or diuretic-intractable ascites - Informed consent before enrollment

Exclusion criteria

Exclusion criteria: - Chronic kidney disease who received renal replacement therapy - Acute kidney injury during enrollment - Congestive heart failure and cardiac arrhythmia patient - Patient with cardiac pacemaker devices - Patient with shock - Patient who have injected with contrast media within 2 weeks - Active urinary tract infection - Pregnancy - Patient who have hemodynamic unstable from previous abdominal paracentesis

Design outcomes

Primary

MeasureTime frame
Acute tubular injury in cirrhosis who received abdominal paracentesis Before and after abdominal paracentesis Change of urine TIMP-2.IGFBP-7 In urine

Secondary

MeasureTime frame
CKD progression, mortality in 90 days, Readmission 90 days Decline in GFR, Death and admission times

Countries

Thailand

Contacts

Public ContactAnuchit Suksamai

Gastroenterology and Hepatology unit, Department of Medicine, Phramongkutklao Hospital

Anuchit.suksamai@gmail.com0865344609

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026