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Cold therapy for pain relief during and post amniocentesis procedure ; randomized controlled trial

Cold therapy for pain relief during and post amniocentesis procedure

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20191115002
Enrollment
480
Registered
2019-11-15
Start date
2019-10-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

amniocentesis in pregnant women aged between 18&#45

Interventions

cold therapy before amniocentesis,Placebo,cold therapy before and after amniocentesis,cold therapy after amniocentesis
Experimental Device,No Intervention Drug,Experimental Device,Experimental Device
cold therapy before amniocentesis,no cold therapy,cold therapy before and after amniocentesis,cold therapy after amniocentesis

Sponsors

Faculty of Medicine, Thammasat Univeristy funding
Lead Sponsor
Faculty of Medicine&#44
Collaborator
Thammasat Univeristy funding
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women who aged 18-45 2. Pregnant women at gestational age between 15-20 weeks and want to have prenatal diagnosis by amniocentesis 3. No fetal anomaly by trans abdominal ultrasound scan

Exclusion criteria

Exclusion criteria: 1. Twin pregnancy 2. Seen anomalies by trans abdominal ultrasound scan 3. More than 1 time of amniocentesis in this visit 4. Pregnant women who have cold urticaria 5. Pregnant women who have Reynuad phenomenon 6. Pregnant women who have skin infection at the area of amniocentesis 7. Pregnant women who have phycosis 8. Denied to participate

Design outcomes

Primary

MeasureTime frame
pain during and post amniocentesis before, during and after amniocentesis Visual analog scale score

Secondary

MeasureTime frame
patient satisfaction post amniocentesis Visual analog scale score

Countries

Thailand

Contacts

Public ContactSawanya Benchahong

Thammasat university

knotb@hotmail.com+66869836433

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026