Vitamin D receptor polymorphism Chronic HBV infection HBV carrier with low viral load Chronic hepatitis Vitamin D receptor polymorphism Chronic HBV infection HBV carrier with low viral load Chronic hepatitis
Conditions
Interventions
Patients with chronic hepatitis B infection that have HBV viral load less than 2,
000 IU/ml,Patients with chronic hepatitis B infection that have HBV viral load more than 2,
000 IU/ml or ALT > upper normal limit or evidence of significant liver fibrosis
Basic Science,Basic Science
HBV carrier with low viral load,Chronic hepatitis
Sponsors
Department of medicine
Chulolongkorn Memorial hospital
Eligibility
Sex/Gender
All
Age
30 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients with chronic HBV infection defined by HBsAg positive more than 6 months.
Exclusion criteria
Exclusion criteria: - pregnancy - patients with the conditions that may alter the immune system, for example; HIV infection, cancer, autoimmune disease, receiving immunosuppressive drugs and active infection. - HCV and HIV co-infection - HBV infected patients with decompensated cirrhosis and hepatocellular carcinoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single nucleotide polyomorphism(SNP) during recruitment real time PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| Haplotype during recruitment Sequence of SNP | — |
Countries
Thailand
Contacts
Public ContactProoksa Ananchuensook
Devision of gastroenterology and herpetology, faculty of medicine, King Chulalongkorn Memorial hospi
Outcome results
None listed