Pediatric patients requiring endotracheal intubation in PICU Respiratory failure Pediatric Respiratory failure Endotracheal intubation Apneic oxygenation Intensive care unit
Conditions
Interventions
After sedation,
patient will be put on nasal cannula and given dry oxygen flow 2 L/kg/min (max 40 L/min). After which,
NMBA will be given and endotracheal intubation will be performed. Nasal cannula will be removed after successful intubation.,After sedation and neuromuscular blockade,
patient will be intubated as usual method.
Experimental Procedure/Surgery,No Intervention No treatment
Apneic oxygenation,Control
Sponsors
None
Eligibility
Sex/Gender
All
Age
31 Days to 18 Years
Inclusion criteria
Inclusion criteria: Patients age 31 days to 18 years who will be intubated in PICU with neuromuscular blocking agent (NMBA) use
Exclusion criteria
Exclusion criteria: 1.Uncorrected cyanotic congenital heart disease 2.Known difficult airway 3.Patients who urgently require intubation that the study process will cause harm due to the delay in intubation 4.Patients with unstable vital signs or hypotensive shock 5.Known or suspected pneumothorax or pneumomediastinum 6.Severe abdominal distention 7.Known or suspected basal skull fracture 8.Patients whom NMBA was not used 9.Tracheostomized patients 10.Patients who have endotracheal tube change (not new intubation)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen desaturation During intubation Pulse oximetry < 90% | — |
Secondary
| Measure | Time frame |
|---|---|
| Severe oxygen desaturation During intubation Pulse oximetry < 80%,Lowest oxygen saturation During intubation up to 2 minutes after successful intubation Pulse oximetry,Hypotension that requires treatment with medication or fluid During intubation Blood pressure measurement,Bradycardia that requires medication During intubation Electrocardiogram monitoring,Cardiac arrest During intubation Electrocardiogram monitoring,Air leak syndrome During and immediately after intubation Chest X-ray showing pneumothorax, pneumomediastinum or pneumoperitoneum,Abdominal distention During and immediately after intubation Physical exam | — |
Countries
Thailand
Contacts
Public ContactSuvikrom Law
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed