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Effect of Ketamine Co-Induction with Propofol on Body Temperature and Hemodynamics in Neurosurgery: A Randomized Controlled Trial

Effect of Ketamine Co-Induction with Propofol on Body Temperature and Hemodynamics in Neurosurgery: A Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20191031003
Enrollment
Unknown
Registered
2019-10-31
Start date
2019-10-18
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male or female&#44

Interventions

Ketamine Co&#45
Induction with Propofol ,Normal Saline Co&#45
Induction with Propofol
Active Comparator Drug,Placebo Comparator Drug
Ketmain group,Control group

Sponsors

Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Neurosurgical condition e.g. brain tumor, spinal cord tumor Receive general anesthesia for neurosurgery at least 2 hours ASA (American Society of Anesthesiologists) class I - II

Exclusion criteria

Exclusion criteria: 1. Baseline body temperature > 37.3 degree celsius 2. Increased intracranial pressure with Glasgow coma scale (GCS) score 30 kg/m2)

Design outcomes

Primary

MeasureTime frame
Effect of Ketamine Co-Induction with Propofol on Body Temperature every 2-30 minutes depended on the time collecting degree celsius—

Secondary

MeasureTime frame
Effect of Ketamine Co-Induction with Propofol on Hemodynamics every 2-30 minutes depended on the time collecting mmHg—

Countries

Thailand

Contacts

Public ContactAnanchanok Saringcarinkul

Department of Anesthesiology, Faculty of Medicine, Chiang Mai University

asaringc@yahoo.com0946296109

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026